Study of Normal Values in Coagulation Profile

0
Rate this post

Study of Normal Values in Coagulation Profile

Kritsana Pathepchotiwong, M.Sc..*,

Pornsri Tantiniti, M.Sc.*,

Chokdee Sutthithampanich, B.Sc.*

Abstract

                The objective of the present work was to study normal values of hemostasis parameters in healthy volunteers using Behring Coagulation Timer (BCT). Plasma was divided into 2 parts fresh plasma and lyophilized plasma. It was found that the mean + SD of prothrombin time (PT) and activated partial thromboplastin time (APTT) in fresh plasma (n=37) were 11.95 + 0.7 and 40.52 + 5.30 seconds respectively. The means + SD of coagulation factors I, II, VII, VIII and IX were 2.55 + 0.73 g/l (n=36), 82.28 + 10.28 per cent (n=37), 82.79 + 19.36 per cent (n=32), 89.13 + 24.17 per cent (n=37), 94.11 + 16.29 per cent (n=31) respectively. The normal ranges (p5-p95) of PT, APTT and coagulation factors I, II, VII, VIII and IX were 10.8-13.3 sec, 31.4-48.0 sec and 1.82-4.65 g/l, 64.83-96.5 per cent, 46.88-113.5 per cent, 52.44-127.61 per cent and 67.87- 116.94 per cent respectively. Comparison of PT, APTT between fresh plasma and lyophilized plasma were statistically different (Wilcoxon match-pair signed rank test, p